HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycidol → N,N,N'-Tri-(2,3-dihydroxypropyl)trimethylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycidol | HCID 11164 | — |
| Reactant | 3,3'-[(3-Aminopropyl)azanediyl]di(propane-1,2-diol) | HCID 23467798 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N,N,N'-Tri-(2,3-dihydroxypropyl)trimethylenediamine | HCID 23467815 | — |
Reaction Steps
N,N-di-(2,3-dihydroxypropyl)trimethylenediamine (11.1 g., 0.05 mole) was dissolved in 125 ml. of methanol and heated under reflux with agitation. Glycidol (3.7 g., 0.05 mole) was added dropwise over a period of 1.5 hour and the solution mixed an additional hour at 60°-80° C. The methyl alcohol and other volatiles were removed by stripping under reduced pressure to leave the product suitable for use in the next steps.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049417 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-120005fc13c8499b98002574d21aad10 |
| Source note | uspto-grants-1977_09 |