反应详情

1.2 g. of N-butyl-acetamidine (Bp.: 76°-78° C./0.4 torr) are dissolved in 50 ml of anhydrous ethanol, whereafter 1.4 g. of 5-diazo-imidazole-4-carboxamide are added at 25° C. under stirring within 10 minutes. After 2.5 hours the orange-colored solution is clarified with activated characoal and evaporated in vacuo. 2.6 g. of a slowly crystallizing resin are obtained, which is twice crystallized from an ethanol-acetone mixture. Thus, a colorless, crystalline product, the 5-[3-n-butyl-3-(alpha-iminoethyl)-1-triazeno]-imidazole-4-carboxamide, melting at 191° C., is obtained (decomposition)

1. waitAfter 2.5 hours the orange-colored solution is clarified with activated characoal
2. customevaporated in vacuo
3. customof a slowly crystallizing resin are obtained
4. customwhich is twice crystallized from an ethanol-acetone mixture