Ethylenediamine → HCID 21409973, compound

Participants

Reaction Steps

A solution of 6.4 g. (20 mmole) of 2-(2-chloro-N-methyl-acetamido)-5-chlorobenzophenone, 12.0 g. (0.2 mole) of ethylenediamine, 50 ml. of triethylamine and 250 ml. of ethanol was heated at reflux for 20 hours. The reaction mixture was concentrated to a residue which was partitioned between ether and water. The ether layer was washed with water, dried and concentrated to a small amount of liquid which was treated with a small amount of ethanol to give upon standing the above-titled product as colorless crystals, m.p. 164°-167°.

Provenance & Evidence