HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride, 3,4-dichloro- → AH 7921 hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride, 3,4-dichloro- | HCID 76403 | — |
| Reactant | 1-(Aminomethyl)-N,N-dimethylcyclohexan-1-amine | HCID 2113403 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | AH 7921 hydrochloride | HCID 21409948 | — |
Reaction Steps
A mixture of 1-aminomethylcyclohexyl dimethylamine (1.0 g.), 3,4-dichlorobenzoyl chloride (2 ml) and pyridine (10 ml) was allowed to stand at room temp. for 1 hr. The pale yellow solid produced was filtered and recrystallised from ethanol/ether to give colourless microneedles of 1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine hydrochloride m.p. 215°-16°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049663 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-6b3951fecbc4400ab0078d0420cdfbfd |
| Source note | uspto-grants-1977_09 |