HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → N-{[1-(Dimethylamino)cyclohexyl]methyl}benzamide hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 1-(Aminomethyl)-N,N-dimethylcyclohexan-1-amine | HCID 2113403 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-{[1-(Dimethylamino)cyclohexyl]methyl}benzamide hydrochloride (1:1) | HCID 21409912 | — |
Reaction Steps
A mixture of 1-aminomethylcyclohexyldimethylamine (1.5 g), benzoyl chloride (3 ml) and pyridine (10 ml) was allowed to stand at room temperature for 1 hr. The crystalline mass was filtered and recrystallised several times from 95% ethanol to give colourless prisms of 1-benzamidomethylcyclohexyldimethylamine hydrochloride m.p. 245°-6°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049663 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-a9fd878353ac450f97e391d77f20370c |
| Source note | uspto-grants-1977_09 |