4-Hydroxymethylpyridin-2-carboxylic acid isobutyl ester → 2-benzyl-6-bromo-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid 2-isobutoxycarbonylpyridin-4-ylmethyl Ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9](=[O:28])[c:10]2[cH:11][cH:12][c:13]([Br:27])[cH:14][c:15]2[c:16](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:17]1[C:18](=[O:19])[OH:20].[CH2:29]([CH:30]([CH3:31])[CH3:32])[O:33][C:34](=[O:35])[c:36]1[n:37][cH:38][cH:39][c:40]([CH2:42][OH:43])[cH:41]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9](=[O:28])[c:10]2[cH:11][cH:12][c:13]([Br:27])[cH:14][c:15]2[c:16](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:17]1[C:18]([O:19][CH2:42][c:40]1[cH:39][cH:38][n:37][c:36]([C:34]([O:33][CH2:29][CH:30]([CH3:31])[CH3:32])=[O:35])[cH:41]1)=[O:20]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7b829f03f1a84cb9bc0a48c9302ca269
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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