HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride, 3,4,5-trimethoxy- → HCID 21409951, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride, 3,4,5-trimethoxy- | HCID 78282 | — |
| Reactant | 1-[1-(4-METHYLPIPERAZIN-1-YL)CYCLOHEXYL]METHANAMINE | HCID 7018132 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 21409951 | HCID 21409951 | 45.4% |
Reaction Steps
A solution of 3,4,5-trimethoxybenzoyl chloride (2.2 g;) in dry benzene (25 ml) and a solution of 1-[1-(aminomethyl)cyclohexyl]-4-methyl piperazine (2.0g;) in dry benzene (25 ml) were mixed and heated under reflux for 1 hr. The solid which formed was filtered, washed with benzene and was crystallised from isopropanol-ether to give 1-[1-(3,4,5-trimethoxybenzamidomethyl)cyclohexyl]-4-methyl piperazine hydrochloride (1.9 g., 45.4%) m.p. 208°-9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049663 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-3f7727fd911a4ed0a79ad6b87116e2f9 |
| Source note | uspto-grants-1977_09 |