Potassium Cyanide → HCID 21409853, compound

Participants

Reaction Steps

A solution of potassium cyanide (34.20 g.,) in water (75 ml.) was added dropwise to a stirred solution of dimethylamine hydrochloride (40.8 g.,) and hexane-2-one (50 g., 0.5 mole) in water (60 ml.) cooled in an ice-water bath. The mixture was vigorously stirred for 24 hrs., diluted with water (200 ml.) and extracted with ether (4 × 200 ml.). The combined ether extracts were washed with water (4 × 200 ml.), dried (Na2SO4) and evaporated to leave a colourless oil which was distilled at 12 mm. to give a colourless oil which when distilled gave 2-methyl-2-dimethylamino-hexanenitrile as a colourless oil (51.547 g., 67%, b.p. 92°/12 mm).

Provenance & Evidence