反应详情

1-Cyano-N,N-dimethyl cyclohexylamine (10 g.) was added portionwise to conc. sulphuric acid (20 ml.) and the solution left for 15 minutes. The cooled solution was diluted with ice-cold water and neutralised with barium hydroxide octahydrate. The mixture was filtered on hyflo and the filtrate evaporated to dryness when the residual oil (9.1 g., 81%) crystallised on standing. Recrystallisation from petrol (80/100) afforded 1-dimethylamino cyclohexane carboxamide m.p. 65°69°.

1. filtrationThe mixture was filtered on hyflo
2. customthe filtrate evaporated to dryness when the residual oil (9.1 g., 81%)
3. customcrystallised
4. customRecrystallisation from petrol (80/100)