HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → HCID 178419246, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | (3-Mercaptopropyl)ammonium chloride | HCID 197870 | — |
| Reactant | 4-Methylimidazol-5-ylmethanolhydrochloride | HCID 3084707 | — |
| Product | HCID 178419246 | HCID 178419246 | — |
Reaction Steps
A solution of homocysteamine hydrochloride (22.0 g.) and 4-hydroxymethyl-5-methylimidazole hydrochloride (25.6 g.) in aqueous hydrobromic acid (500 ml.) was heated under reflux for 1 hour. Concentration under reduced pressure, followed by recrystallisation from methanol-isopropyl alcohol afforded 4-methyl-5-[(3-aminopropyl)thiomethyl]-imidazole dihydrobromide (24.5 g.), m.p. 200.5-202.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049672 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-37b2f72c142f4160bcdf2b4d29a529b7 |
| Source note | uspto-grants-1977_09 |