Ethylenediamine → HCID 178484971, compound

HRID 2072059Notes

Reaction equation

HRID 2072059 reaction equation
BrCCC1C=CNN=1.C(N)CN.[NH:13]1[CH:17]=[CH:16][C:15]([CH2:18][NH:19][CH2:20][CH2:21][NH2:22])=[N:14]1.[C:23]([NH:25][C:26](=[N:29][CH3:30])SC)#[N:24]>>[C:23]([NH:25][C:26]([NH:29][CH3:30])=[N:22][CH2:21][CH2:20][NH:19][CH2:18][C:15]1[CH:16]=[CH:17][NH:13][N:14]=1)#[N:24]

Participants

5

Reactant 4

HCID 3301EthylenediamineHCID 1111031-Cyano-2,3-dimethylisothioureaHCID 178419532HCID 178419532, compoundHCID 178511340HCID 178511340, compound

Product 1

HCID 178484971HCID 178484971, compound

Procedure

Reacting 3-bromethylpyrazole with ethylenediamine by the procedure of Example 34 and reacting the resulting N-(3-pyrazolylmethyl)ethylenediamine with N-cyano-N',S-dimethylisothiourea by the procedure of Example 3(d) gives N-cyano-N'-methyl-N"-[2-(3-pyrazolylmethylamino)ethyl]guanidine. Hydrolysis of this compound by the procedure of Example 3(e) gives N-methyl-N'-[2-(3-pyrazolylmethylamino)ethyl]guanidine trihydrochloride.

Sources & evidence

ORD record
ord-b685fa4ab18849929219e63c2e0a5583
Source dataset
uspto-grants-1977_09
Patent number
US04049672

Reaction notes

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