HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isothiocyanate → N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isothiocyanate | HCID 10966 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | N-(pyrazinylmethyl)ethylenediamine | HCID 13910894 | — |
| Product | N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine | HCID 54105532 | — |
Reaction Steps
Reacting N-(2-pyrazinylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3 and chromatographing gives N-ethyl-N'-[2-(2-pyrazinylmethylamino)ethyl]thiorea. Reacting this thiourea with lead cyananmide by the procedure of Example 3 gives N-cyano-N'-ethyl-N"-[2-(2-pyrazinylmethylamino)ethyl]-guanidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049672 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-961216af9861418fb5ca6fc250fd0d6d |
| Source note | uspto-grants-1977_09 |