HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-ethyl-N'-[2-(2-thiazolylmethylamino)ethyl]thiourea → N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylamino)ethyl]guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-ethyl-N'-[2-(2-thiazolylmethylamino)ethyl]thiourea | HCID 20567447 | — |
| Reactant | CH2N2Pb | HCID 22262466 | — |
| Product | N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylamino)ethyl]guanidine | HCID 54278387 | — |
Reaction Steps
Reacting N-(2-thiazolylmethyl)ethylenediamine with ethyl isothiocyanate by the procedure of Example 3(b) and then chromatographing gives N-ethyl-N'-[2-(2-thiazolylmethylamino) ethyl]thiourea. Reacting this thiourea with lead cyanamide by the procedure of Example 3(b) gives N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylamino)ethyl]-guanidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049672 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-55a4154364164ab180e7916ebd476202 |
| Source note | uspto-grants-1977_09 |