Potassium cyanate → Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-

HRID 2072151Notes

Reaction equation

HRID 2072151 reaction equation
Cl.[O:2]=[C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]([NH2:13])[CH2:5][CH2:4]1.[O-:14][C:15]#[N:16].[K+]>O>[O:2]=[C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:6]([NH:13][C:15]([NH2:16])=[O:14])[CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 11378442Potassium cyanateHCID 203273204-Amino-1,2,3,4-tetrahydronaphthalen-1-one hydrochloride

Product 1

HCID 3628438Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A sample of 26.55 g. of 1,2,3,4-tetrahydro-4-oxo-1-naphthylamine hydrochloride is dissolved in 250 ml. water and a solution of 21.8 g. of potassium cyanate in 75 ml. of water added. The reaction mixture is stirred for 72 hours, the precipitate formed in the reaction is collected by filtration and dried to afford 21.45 g. of the title compound, m.p. 225° C. (dec.).

Workup

  1. customthe precipitate formed in the reaction
  2. filtrationis collected by filtration
  3. customdried
  4. customto afford 21.45 g

Sources & evidence

ORD record
ord-aa79dccce154404c8370a8d27ceb76cc
Source dataset
uspto-grants-1977_09
Patent number
US04049717

Reaction notes

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