1-(4-Chlorobutyl)-1-methyl-5-methoxy-2tetralone → 6,7,8,9,10,11-Hexahydro-1-Methoxy-5-Methyl-5,10-Methano-5H-Benzocyclononen-12-One

HRID 2072162Notes

Reaction equation

HRID 2072162 reaction equation
COC1C=CC2CC3C(=O)C(C)(C=2C=1)CCCC3.Cl[CH2:20][CH2:21][CH2:22][CH2:23][C:24]1([CH3:37])[C:33]2[C:28](=[C:29]([O:34][CH3:35])[CH:30]=[CH:31][CH:32]=2)[CH2:27][CH2:26][C:25]1=[O:36]>>[CH3:35][O:34][C:29]1[C:28]2[CH2:27][CH:26]3[C:25](=[O:36])[C:24]([CH3:37])([C:33]=2[CH:32]=[CH:31][CH:30]=1)[CH2:23][CH2:22][CH2:21][CH2:20]3

Participants

3

Reactant 2

HCID 214100741-(4-Chlorobutyl)-1-methyl-5-methoxy-2tetraloneHCID 214101236,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen 12-one

Product 1

HCID 214101036,7,8,9,10,11-Hexahydro-1-Methoxy-5-Methyl-5,10-Methano-5H-Benzocyclononen-12-One

Procedure

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl-5,10-methano-5H-benzocyclononen-12-one, there is obtained from 40.5 g. of 1-(4-chlorobutyl)-1-methyl-5-methoxy-2-tetralone, 21.5 g. of the title product, b.p. 130° to 135° C. (0.3 mm.).

Workup

  1. customthere is obtained from 40.5 g

Sources & evidence

ORD record
ord-0b285be3e15a4ae0bc67177b60aaab5b
Source dataset
uspto-grants-1977_09
Patent number
US04049701

Reaction notes

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