HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 20509742, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 20509762 | HCID 20509762 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 20509742 | HCID 20509742 | — |
Reaction Steps
Reaction of equimolar amounts of phosphorus oxychloride, 3-(p-anisidinomethyl)-5-bromoindole, 2-pyrrolidinone and triethylamine in 1,2-dichloroethane according to the procedure of Example 35 provides 5-bromo-3-[(N-[1-pyrrolin-2-yl]-p-anisidino)methyl]indole. Acidification of the free base with ethanolic hydrogen chloride provides 5-bromo-3-[(N-[1-pyrrolin-2-yl]-p-anisidino)methyl]indole hydrochloride, m.p. 205.5°-207.5° C. (corr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04049714 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-6c45bc3ce0c94497928d4d5662895318 |
| Source note | uspto-grants-1977_09 |