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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2072179Generated: November 3, 2026

4,6-Diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 6-amino-6,7-dideoxyheptopyranoside → 4,6-Diamino-3-((3-deoxy-3-(methylamino)pentopyranosyl)oxy)-2-hydroxycyclohexyl 2-amino-2-deoxyhexopyranoside

https://huagongshe.com/reaction/2072179

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,6-Diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 6-amino-6,7-dideoxyheptopyranosideHCID 3034288—
ReactantGentamicin BHCID 11754987—
Reactant36889-17-5HCID 15574862—
ReactantHCID 44264618HCID 44264618—
Product4,6-Diamino-3-((3-deoxy-3-(methylamino)pentopyranosyl)oxy)-2-hydroxycyclohexyl 2-amino-2-deoxyhexopyranosideHCID 86474—

Reaction Steps

In like manner, the sulfate salt of gentamicin B, gentamicin B1 and gentamicin X may be prepared. In order to prepare sulfate salts of a mixture of gentamicin A, B, B1 and X, the lyophilized or spray dried product of Example 2 is treated as described in this example.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04049796
Source datasetuspto-grants-1977_09
ORD IDord-6c778a8eea1045a8b34508aae843e673
Source noteuspto-grants-1977_09