2-(Methylsulfinyl)-2'-(4-benzyloxyanilino)-5'-methoxyacetophenone → 1-(4-benzyloxyphenyl)-2-phenyl-6-methoxy-4(1H)-quinolone

HRID 2072248Notes

Reaction equation

HRID 2072248 reaction equation
CS(C[C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1NC1C=CC(OC)=CC=1)=O)=O.CS([CH2:25][C:26]([C:28]1[CH:33]=[C:32]([O:34][CH3:35])[CH:31]=[CH:30][C:29]=1[NH:36][C:37]1[CH:42]=[CH:41][C:40]([O:43][CH2:44][C:45]2[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=2)=[CH:39][CH:38]=1)=[O:27])=O>>[CH2:44]([O:43][C:40]1[CH:41]=[CH:42][C:37]([N:36]2[C:29]3[C:28](=[CH:33][C:32]([O:34][CH3:35])=[CH:31][CH:30]=3)[C:26](=[O:27])[CH:25]=[C:5]2[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:38][CH:39]=1)[C:45]1[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=1

Participants

3

Reactant 2

HCID 213984892-(Methylsulfinyl)-2'-(4-benzyloxyanilino)-5'-methoxyacetophenoneHCID 213985852-(Methylsulfinyl)-2'-(4-methoxyanilino)acetophenone

Product 1

HCID 213985241-(4-benzyloxyphenyl)-2-phenyl-6-methoxy-4(1H)-quinolone

Procedure

Following a procedure similar to that described in Example 12, Procedure 3, but substituting for 2-(methylsulfinyl)-2'-(4-methoxyanilino)acetophenone an equivalent amount of 2-(methylsulfinyl)-2'-(4-benzyloxyanilino)-5'-methoxyacetophenone there can be obtained 1-(4-benzyloxyphenyl)-2-phenyl-6-methoxy-4(1H)-quinolone.

Sources & evidence

ORD record
ord-5fdb92fdb28143deabfc34160c19d35b
Source dataset
uspto-grants-1977_09
Patent number
US04049715

Reaction notes

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