1-(4-benzyloxyphenyl)-2-phenyl-6-methoxy-4(1H)-quinolone → 1-(4-Hydroxyphenyl)-2-phenyl-6-methoxy-1,2,3,4-tetrahydroquinoline

HRID 2072249Notes

Reaction equation

HRID 2072249 reaction equation
COC1C=CC(N2C3C(=CC=CC=3)C(=O)C=C2C2C=CC=CC=2)=CC=1.C([O:33][C:34]1[CH:39]=[CH:38][C:37]([N:40]2[C:49]3[C:44](=[CH:45][C:46]([O:50][CH3:51])=[CH:47][CH:48]=3)[C:43](=O)[CH:42]=[C:41]2[C:53]2[CH:58]=[CH:57][CH:56]=[CH:55][CH:54]=2)=[CH:36][CH:35]=1)C1C=CC=CC=1>>[OH:33][C:34]1[CH:35]=[CH:36][C:37]([N:40]2[C:49]3[C:44](=[CH:45][C:46]([O:50][CH3:51])=[CH:47][CH:48]=3)[CH2:43][CH2:42][CH:41]2[C:53]2[CH:54]=[CH:55][CH:56]=[CH:57][CH:58]=2)=[CH:38][CH:39]=1

Participants

3

Reactant 2

HCID 213985241-(4-benzyloxyphenyl)-2-phenyl-6-methoxy-4(1H)-quinoloneHCID 213985651-(4-methoxyphenyl)-2-phenyl-4(1H)-quinolone

Product 1

HCID 213986091-(4-Hydroxyphenyl)-2-phenyl-6-methoxy-1,2,3,4-tetrahydroquinoline

Procedure

Following a procedure similar to that described in Example 7, Procedure 2, but substituting for 1-(4-methoxyphenyl)-2-phenyl-4(1H)-quinolone an equivalent amount of 1-(4-benzyloxyphenyl)-2-phenyl-6-methoxy-4(1H)-quinolone there can be obtained 1-(4-hydroxyphenyl)-2-phenyl-6-methoxy-1,2,3,4-tetrahydroquinoline.

Sources & evidence

ORD record
ord-9db1ff6cf1e444dabfe83a1afbc0f4f8
Source dataset
uspto-grants-1977_09
Patent number
US04049715

Reaction notes

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