1-{4-[2-(Diethylamino)ethoxy]phenyl}-2-phenyl-4(1H)-quinolone → 1-{4-[2-(Diethylamino)ethoxy]phenyl}-2-phenyl-1,2,3,4-tetrahydroquinoline

HRID 2072251Notes

Reaction equation

HRID 2072251 reaction equation
COC1C=CC(N2C3C(=CC=CC=3)C(=O)C=C2C2C=CC=CC=2)=CC=1.[CH2:26]([N:28]([CH2:55][CH3:56])[CH2:29][CH2:30][O:31][C:32]1[CH:37]=[CH:36][C:35]([N:38]2[C:47]3[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=3)[C:41](=O)[CH:40]=[C:39]2[C:49]2[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=2)=[CH:34][CH:33]=1)[CH3:27]>>[CH2:55]([N:28]([CH2:26][CH3:27])[CH2:29][CH2:30][O:31][C:32]1[CH:37]=[CH:36][C:35]([N:38]2[C:47]3[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=3)[CH2:41][CH2:40][CH:39]2[C:49]2[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=2)=[CH:34][CH:33]=1)[CH3:56]

Participants

3

Reactant 2

HCID 213984861-{4-[2-(Diethylamino)ethoxy]phenyl}-2-phenyl-4(1H)-quinoloneHCID 213985651-(4-methoxyphenyl)-2-phenyl-4(1H)-quinolone

Product 1

HCID 213984881-{4-[2-(Diethylamino)ethoxy]phenyl}-2-phenyl-1,2,3,4-tetrahydroquinoline

Procedure

By following a procedure similar to that described in Example 7 (Procedure 2) and substituting for 1-(4-methoxyphenyl)-2-phenyl-4(1H)-quinolone an equivalent amount of 1-{4-[2-(diethylamino)ethoxy]phenyl}-2-phenyl-4(1H)-quinolone there can be obtained 1-{4-[2-(diethylamino)ethoxy]phenyl}-2-phenyl-1,2,3,4-tetrahydroquinoline.

Sources & evidence

ORD record
ord-dbc9e825174d4ae1ade0060509f5bc60
Source dataset
uspto-grants-1977_09
Patent number
US04049715

Reaction notes

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