HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → HCID 22769951, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | 4H-Pyran-3-carboxylic acid, 2,6-dimethyl-4-oxo-, methyl ester | HCID 12281371 | — |
| Catalyst | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 22769951 | HCID 22769951 | 46.8% |
Reaction Steps
40 g of 3-carbomethoxy-2,6-dimethylpyr-4-one and 30.2 g of 4-chloroaniline are dissolved in 400 ml of toluene along with 400 mg of p-toluenesulfonic acid monohydrate. The reaction mixture is refluxed for four hours. The solvent is removed and the product crystallized from ether to yield 30 g of N-(4-chlorophenyl)-3-carbomethoxy-2,6-dimethylpyrid-4-one (m.p. 189°-90°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051142 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-a580e2bca85b4ff7b5cd8acf32593bad |
| Source note | uspto-grants-1977_09 |