HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3-Benzylmercapto-4-chlorocarbonyl benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Benzylmercapto-4-carboxy benzaldehyde | HCID 53916835 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Benzylmercapto-4-chlorocarbonyl benzaldehyde | HCID 53682313 | — |
Reaction Steps
To a solution containing 23.2 g of 3-benzylmercapto-4-carboxy benzaldehyde in 250 ml of methylene chloride is added 15 ml of thionyl chloride and 0.5 ml of dimethylformamide. The reaction mixture is refluxed for 6-7 hours, then evaporated to dryness. Crystallization from 100 ml of ether yielded 27.0 g of 3-benzylmercapto-4-chlorocarbonyl benzaldehyde (a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051148 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-44e2cdc2638042c2b7194d606af3c913 |
| Source note | uspto-grants-1977_09 |