HCID 53699476, compound → 6-chloro-1H-indazol-3-amine

HRID 2072403Notes

Reaction equation

HRID 2072403 reaction equation
COC([N:5]1[C:13]([NH2:14])=[C:12]2[C:7]([CH:8]=[C:9]([Cl:15])[CH:10]=[CH:11]2)=[N:6]1)=O>COC(OC(OC)=O)=O>[NH2:14][C:13]1[C:12]2[C:7](=[CH:8][C:9]([Cl:15])=[CH:10][CH:11]=2)[NH:6][N:5]=1

Participants

3

Reactant 1

HCID 53699476HCID 53699476, compound

Product 1

HCID 856286-chloro-1H-indazol-3-amine

Reagents, catalysts & solvents 1

HCID 3086Dimethyl dicarbonateSolvent

Procedure

Analogously to Example 1, 0.1 mol of 3-amino-6-chloroindazole in 50 ml of pyrocarbonic acid dimethyl ester gives 3-amino-6-chloroindazole-2-carboxylic acid methyl ester (melting point: 198°-200° C; 90% of theory) in 30 minutes at 30°-50° C.

Sources & evidence

ORD record
ord-53389eb3172e4c07a5cb28ae9df00686
Source dataset
uspto-grants-1977_09
Patent number
US04051252

Reaction notes

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