Dimethylcarbamoyl Chloride → HCID 53809421, compound

Participants

Reaction Steps

0.04 mol of 3-dimethylamino-6-chloroindazole and 0.04 mol of sodium amide in 50 ml of toluene are heated to the boil for 1 hour. 0.04 mol of dimethylcarbamic acid chloride is added dropwise at 60° C and this temperature is maintained for 7 hours, while stirring. After cooling, the solution is filtered and evaporated in vacuo. Distillation of the residue gives 3-dimethylamino-6-chloroindazole-1-carboxylic acid dimethylamide (boiling point0.35 170° C, melting point: 65°-66° C; 75% of theory).

Provenance & Evidence