HCID 54133871, compound → HCID 53728058, compound

HRID 2072420Notes

Reaction equation

HRID 2072420 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([Cl:15])[CH:13]=2)[C:8]([NH:16]C=O)=[N:7]1)=[O:5])[CH3:2]>C(O)=O>[CH2:1]([O:3][C:4]([N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([Cl:15])[CH:13]=2)[C:8]([NH2:16])=[N:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 1

HCID 54133871HCID 54133871, compound

Product 1

HCID 53728058HCID 53728058, compoundYield 71%

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

Analogously to Example 56, 0.085 mol of 3-amino-6-chloroindazole-1-carboxylic acid ethyl ester and 100 ml of formic acid produce 3-formylamino-6-chloroindazole-1-carboxylic acid ethyl ester in 3.5 hours at 100° C (melting point 227°-230° (decomposition), yield: 71% of theory).

Sources & evidence

ORD record
ord-8be5e89176e044869682520f377b1670
Source dataset
uspto-grants-1977_09
Patent number
US04051252

Reaction notes

Loading…