HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → N-(4-chlorophenyl)-N'-cyclohexylthiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | 4-Chlorophenyl isothiocyanate | HCID 16480 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | N-(4-chlorophenyl)-N'-cyclohexylthiourea | HCID 709206 | — |
Reaction Steps
To a solution of cyclohexylamine (1.75 g.) in chloroform (15 ml.) was added dropwise with stirring a solution of p-chlorophenylisothiocyanate (3.0 g.) in chloroform (15 ml.) at room temperature. After stirring 3 hours, the white solid was filtered off, washed with a little CHCl3 and recrystallised from toluene to give 1-cyclohexyl-3-(p-chlorophenyl)thiourea, m.p. 179°-180°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051256 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-a673fd332d83447d8cb2b4f49c587923 |
| Source note | uspto-grants-1977_09 |