反应详情

A mixture of 15 grams (0.064 mole) of α-acetoxy-p-pivaloyl toluene and 15 grams (0.278 mole) of potassium hydroxide in 150 milliliters of ethanol and 50 milliliters of water is refluxed for four hours. The solvent is removed in vacuo, and the residue is treated with ether and water. The ether is separated and the water is again extracted with ether. The ether layers are combined, decolorized with charcoal, dried over magnesium sulfate, filtered and evaporated. The resulting yellow oil is distilled in vacuo to give p-pivaloyl benzyl alcohol (b.p. 100°-105° C./0.1 mm).

1. temperatureis refluxed for four hours
2. customThe solvent is removed in vacuo
3. additionthe residue is treated with ether and water
4. customThe ether is separated
5. extractionthe water is again extracted with ether
6. dry with materialdried over magnesium sulfate
7. filtrationfiltered
8. customevaporated
9. distillationThe resulting yellow oil is distilled in vacuo