Ethanol → HCID 131710912, compound

Participants

Reaction Steps

A mixture comprising 6.0 g 6-chloro-α-tetralone, 3.5 g dimethylamine hydrochloride, 1.3 g paraformaldehyde, and 7 ml 95% ethanol containing 0.07 ml concentrated hydrogen chloride is heated on a steam bath for 1.5 hours. The reaction mixture soon become homogeneous and the paraformaldehyde dissolves. The warm solution is transferred to a wide-mounted flask and is quickly diluted with acetone (90 ml). Cooling this deep purpose solution in the freezer for several hours produces a crystalline mass of light purple needles that is filtered and washed with additional acetone. After drying this material in vacuum, it weighs 6.8 g (76%), melting point 137°-139° C.

Provenance & Evidence