HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131710915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Dimethylamine, hydrochloride | HCID 10473 | — |
| Reactant | 7-Chloro-1,2,3,4-tetrahydronaphthalen-1-one | HCID 256677 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 131710915 | HCID 131710915 | 94% |
Reaction Steps
7-Chloro-α-tetralone (15.0 g), 8.75 g of dimethylamine hydrochloride, 3.25 g of paraformaldehyde, and 17.5 ml of 95% ethanol containing 0.2 ml of concentrated hydrogen chloride are combined and heated on a steam bath for 2 hours. The warm solution is transferred to a wide-mouthed flask, diluted with 200 ml of acetone, and allowed to stand at room temperature for several hours. The resultant crystals are collected and crystallized from acetone/ethanol to give 10.7 g of the title compound, melting point 169°-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051248 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-04c4eb2e0ac04eb2a0c81b61162b7ee5 |
| Source note | uspto-grants-1977_09 |