Methanol → HCID 54343254, compound

HRID 2072562Notes

Reaction equation

HRID 2072562 reaction equation
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[CH2:15][C:16]([O:18]C)=[O:17].C(=O)([O-])[O-].[Na+].[Na+].CO>O>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[CH:6]=[CH:5][C:4]=1[CH2:15][C:16]([OH:18])=[O:17]

Participants

5

Reactant 3

HCID 887MethanolHCID 10340Sodium CarbonateHCID 53970531HCID 53970531, compound

Product 1

HCID 54343254HCID 54343254, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 25 g. of methyl 1,6-dimethoxy-2-naphthylacetate, 15 g. of sodium carbonate, 200 ml. of methanol, and 25 ml. of water are allowed to stand for 24 hours. The reaction mixture is then acidified with 200 ml. of 2N hydrochloric acid and extracted with methylene chloride. The extracts are combined, washed with water, dried over sodium sulfate, and evaporated to yield 1,6-dimethoxy-2-naphthylacetic acid.

Workup

  1. additionA mixture of 25 g
  2. extractionof 2N hydrochloric acid and extracted with methylene chloride
  3. washwashed with water
  4. dry with materialdried over sodium sulfate
  5. customevaporated

Sources & evidence

ORD record
ord-09157cd75950403d9283117733ab62ed
Source dataset
uspto-grants-1977_09
Patent number
US04051233

Reaction notes

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