1-Methylpiperazin-2-one → 6-chloro-1-methyl-2-[5-(4-methyl-3-oxo-piperazin-1-ylmethyl)-pyridin-3-yl]-1H-indole-3-carbonitrile
Reaction equation
[CH3:22][N:23]1[C:24](=[O:29])[CH2:25][NH:26][CH2:27][CH2:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:20]#[N:21])[c:7](-[c:12]3[cH:13][n:14][cH:15][c:16]([CH:18]=[O:19])[cH:17]3)[n:8]([CH3:11])[c:9]2[cH:10]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:20]#[N:21])[c:7](-[c:12]3[cH:13][n:14][cH:15][c:16]([CH2:18][N:26]4[CH2:25][C:24](=[O:29])[N:23]([CH3:22])[CH2:28][CH2:27]4)[cH:17]3)[n:8]([CH3:11])[c:9]2[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-ac8418352e4b42ae847c56a95180586e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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