Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4'-(12-Acetyloxydodecyloxy)biphenyl-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Tetramethylammonium Hydroxide Pentahydrate | HCID 82620 | — |
| 반응물 | 4'-(12-Bromododecyloxy)biphenyl-4-carboxylic acid ethyl ester | HCID 53908401 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4'-(12-Acetyloxydodecyloxy)biphenyl-4-carboxylic acid ethyl ester | HCID 53656928 | 67% |
반응 단계
60 m moles (10.9 g) of tetramethylammonium hydroxide pentahydrate was added to a DMF solution of 60 m moles (3.6 g) of acetic acid, and stirred for one hour, then 50 m moles (24.5 g) of the above 4'-(12-bromododecyloxy)biphenyl-4-carboxylic acid ethyl ester was added thereto, and stirred for 12 hours. After the reaction, the reaction solution was ether extracted. The extrate was concentrated, and then purified by column chromatography, to obtain 15.7 g of 4'-(12-acetyloxydodecyloxy)biphenyl-4-carboxylic acid ethyl ester [m.p. 80.1°-81.5° C⟧ (yield: 67%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04913839 |
| 출처 데이터셋 | uspto-grants-1990_04 |
| ORD ID | ord-b42c5f380ae94eae935561878762c4d5 |
| 출처 메모 | uspto-grants-1990_04 |