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Acetic Acid → 4'-(16-Acetyloxyhexadecyloxy)biphenyl-4-carboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Tetramethylammonium Hydroxide Pentahydrate | HCID 82620 | — |
| 反応物 | 4'-(16-Bromohexadecyloxy)biphenyl-4-carboxylic acid ethyl ester | HCID 54017308 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 4'-(16-Acetyloxyhexadecyloxy)biphenyl-4-carboxylic acid ethyl ester | HCID 54184442 | 69% |
反応手順
60 m moles (10.9 g) of tetramethylammonium hydroxide pentahydrate was added into a DMF solution of 60 m moles (3.6 g) of acetic acid, stirred for one hour, then 50 m moles (27.3 g) of the above 4'-(16-bromohexadecyloxy)biphenyl-4-carboxylic acid ethyl ester was added, and stirred for 12 hours. The reaction solution was ether extracted and concentrated, then purified by column chromatography to obtain 18.1 g of 4'-(16-acetyloxyhexadecyloxy)biphenyl-4-carboxylic acid ethyl ester. (yield: 69%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04913839 |
| 出典データセット | uspto-grants-1990_04 |
| ORD ID | ord-37a7a5624b3b4a9cab60e0a7f289a11f |
| 出典メモ | uspto-grants-1990_04 |