2-(Methylamino)ethanol → HCID 14499658, compound

HRID 2072665Notes

Reaction equation

HRID 2072665 reaction equation
Cl[CH2:2][C:3]([N:5]1[CH2:14][CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6]1)=[O:4].[CH3:15][NH:16][CH2:17][CH2:18][OH:19]>>[O:4]=[C:3]([N:5]1[CH2:14][CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6]1)[CH2:2][N:16]([CH3:15])[CH2:17][CH2:18][OH:19]

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 42646952-chloro-1-(3,4-dihydro-1H-isoquinolin-2-yl)ethanone

Product 1

HCID 14499658HCID 14499658, compound

Procedure

The procedure is similar to that described in Example 6a), reacting 4.78 g (23 mmol) of 2-(2-chloroacetyl)-1,2,3,4-tetrahydroisoquinoline and 3 g (40 mmol) of 2-(methylamino)ethanol.

Sources & evidence

ORD record
ord-92a7f87a014c4bba81760f1fd9a41a53
Source dataset
uspto-grants-1990_04
Patent number
US04914092

Reaction notes

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