Thionyl Chloride → HCID 19860097, compound

HRID 2072666Notes

Reaction equation

HRID 2072666 reaction equation
[O:1]=[C:2]([N:9]1[CH2:18][CH2:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10]1)[CH2:3][N:4]([CH3:8])[CH2:5][CH2:6]O.S(Cl)([Cl:21])=O>C(Cl)(Cl)Cl>[Cl:21][CH2:6][CH2:5][N:4]([CH3:8])[CH2:3][C:2](=[O:1])[N:9]1[CH2:18][CH2:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 14499658HCID 14499658, compound

Product 1

HCID 19860097HCID 19860097, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The procedure is similar to that described in Example 6b), treating 5.6 g of 2-{N-[2-oxo-2-(1,2,3,4-tetrahydro-2-isoquinolyl) ethyl]methylamino}ethanol with an excess of thionyl chloride in chloroform.

Sources & evidence

ORD record
ord-c0b32e1c5dd844828b65a9ad4d959d10
Source dataset
uspto-grants-1990_04
Patent number
US04914092

Reaction notes

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