HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 4-(4-Methoxybenzoyl)thiophene-2-sulfonic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | (4-Methoxyphenyl)(thiophen-3-yl)methanone | HCID 14639065 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(4-Methoxybenzoyl)thiophene-2-sulfonic acid | HCID 14639067 | — |
Reaction Conditions
| Temperature | -10 °C |
|---|
Reaction Steps
9.7 g (0.05 mol) of product from Step A was dissolved in 75 ml CH2Cl2 and cooled to -10° C. Then, 15.3 g (0.15 mol) acetic anhydride was added dropwise followed by the dropwise addition of 5.9 g (0.06 mol) concentrated sulfuric acid. The resulting mixture was stirred at room temperature overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04914111 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-1ba205009e764335ba506a43f202e1fe |
| Source note | uspto-grants-1990_04 |