Ammonium Hydroxide → HCID 14773367, compound

Participants

Reaction Steps

A solution of 1.0 g (0.0032 mol) product from Step B in 30 ml 48% aqueous hydrobromic acid was heated at 85° C. for 4.0 hours. The cooled reaction mixture was made alkaline with concentrated NH4OH solution and was extracted with ether. The organic extract was dried, the solvent evaporated and the resulting residue was purified by flash chromatography on silican gel eluting with 2l % methanol/chloroform to give pure product as a tan solid, m.p. 127°-129° C.

Provenance & Evidence