HCID 19913632, compound → HCID 19860370, compound

HRID 2072777Notes

Reaction equation

HRID 2072777 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]2[O:13][CH2:12][C:11](=O)[N:10]([C:15]([CH3:24])([CH3:23])[CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:9]2)[CH:5]=[CH:6][CH:7]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>CO.C(OCC)(=O)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]2[O:13][CH2:12][CH2:11][N:10]([C:15]([CH3:24])([CH3:23])[CH2:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 19913632HCID 19913632, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 19860370HCID 19860370, compound

Reagents, catalysts & solvents 1

HCID 21584119Ethylacetate methanolSolvent

Procedure

The title compound, m.p. 235° C. (methanol-ethyl acetate), was prepared from 2-[3-chlorophenyl]-4-[1,1-dimethyl-2-phenylethyl]-5-oxomorpholine and lithium aluminium hydride by an analogous procedure to that described in Example 10.

Sources & evidence

ORD record
ord-abc3b82f9fd044b7be9eafc4064fa2c4
Source dataset
uspto-grants-1990_04
Patent number
US04914202

Reaction notes

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