HCID 178433279, compound → HCID 178433265, compound

HRID 2072798Notes

Reaction equation

HRID 2072798 reaction equation
[ClH:1].[CH3:2][C:3]1[N:4]=[CH:5][NH:6][C:7]=1[CH2:8]O>S(Cl)(Cl)=O>[ClH:1].[CH3:2][C:3]1[N:4]=[CH:5][NH:6][C:7]=1[CH2:8][Cl:1]

Participants

3

Reactant 1

HCID 178433279HCID 178433279, compound

Product 1

HCID 178433265HCID 178433265, compound

Reagents, catalysts & solvents 1

HCID 24386Thionyl ChlorideSolvent

Procedure

A solution of 10 g of 4-methyl-5-hydroxymethylimidazole hydrochloride in 25 ml of thionyl chloride was allowed to stir at room temperature overnight. The crystalline product was filtered, washed with chloroform and dried, 11 g.

Workup

  1. filtrationThe crystalline product was filtered
  2. washwashed with chloroform
  3. customdried

Sources & evidence

ORD record
ord-f61bde152ab046fda9e3187e2ec7263b
Source dataset
uspto-grants-1990_04
Patent number
US04914207

Reaction notes

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