N-Boc-3-Chloropropylamine → tert-Butyl (4-chlorobutyl)carbamate

HRID 2072822Notes

Reaction equation

HRID 2072822 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11]Cl)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.[Cl:14][CH2:15]CCCN>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:15][Cl:14])=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 10932310N-Boc-3-ChloropropylamineHCID 190759064-Chlorobutan-1-amine hydrochloride

Product 1

HCID 19758183tert-Butyl (4-chlorobutyl)carbamate

Procedure

This compound, employed as the starting material in example 2, is prepared by following substantially the same procedure described above under (a) but using 4-chloro-butylamine hydrochloride instead of 3-chloro-propylamine hydrochloride.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-46bd64d320764787a966cc5921f0ce0f
Source dataset
uspto-grants-1990_04
Patent number
US04914226

Reaction notes

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