Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 207306Generated: October 29, 2026

Dichloromethane → 7-Isopropyl-2-[4-({8-[4-(trifluoromethyl)benzyl]-2,8-diazaspiro[4.5]dec-2-yl}carbonyl)phenyl]-1,3-benzoxazole-5-carbonitrile

https://huagongshe.com/reaction/207306

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 123062—
Reactant2-[4-(2,8-Diazaspiro[4.5]dec-2-ylcarbonyl)phenyl]-7-isopropyl-1,3-benzoxazole-5-carbonitrileHCID 68745601—
Product7-Isopropyl-2-[4-({8-[4-(trifluoromethyl)benzyl]-2,8-diazaspiro[4.5]dec-2-yl}carbonyl)phenyl]-1,3-benzoxazole-5-carbonitrileHCID 25169586—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-b550d8bb200b47fbaf6070bccad3652b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)