HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4'-(6-Bromohexyloxy)biphenyl-4-carboxylic acid 2-methylbutyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,6-Dibromohexane | HCID 12368 | — |
| Reactant | 4-Hydroxybiphenyl-4-carboxylic acid 2-methylbutyl ester | HCID 67860692 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4'-(6-Bromohexyloxy)biphenyl-4-carboxylic acid 2-methylbutyl ester | HCID 54384507 | 60.3% |
Reaction Steps
70 mmols (19.9 g) of said ester 1a, 100 mmols (24.4 g) of 1,6-dibromohexane and 150 mmols (20.7 g) of potassium carbonate were refluxed in 400 ml of acetone for 8 hours. The reaction mixture was filtered and then purified by column chromatography to obtain 4'-(6-bromohexyloxy)biphenyl-4-carboxylic acid 2-methylbutyl ester (ether 5b; 18.9 g, yield 60%, [α]23D=+2.93 (chloroform)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04915867 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-1977c7f3c6cb4eb09061377b4a944589 |
| Source note | uspto-grants-1990_04 |