Acetonitrile → Benzenesulfonyl chloride, 4-chloro-3-nitro-

Participants

Reaction Steps

To a mixed solution containing 1,280 g of potassium 4-chloro-3-nitrobenzenesulfonate, 1,150 ml of acetonitrile, 250 ml of Sulfolane (tetrahydrothiophene 1,1-dioxide) and 30 ml of dimethylacetamide was dropwise added 1,250 ml of phoshporus oxychloride under an inside temperature at 60° C. to 70° C. After the reaction was continued for 3 hours at 73° C., the reaction mixture was cooled with water, and thereto was slowly added 400 ml of water. The thus obtained product was poured into 5 liters of ice-cold water. The crystalline precipitate was filtered off, washed with water, and dried.

Provenance & Evidence