HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-1-propanone → 3-(Dimethylamino)-2-methyl-1-phenylprop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-1-propanone | HCID 7148 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 3-(Dimethylamino)-2-methyl-1-phenylprop-2-en-1-one | HCID 54075533 | — |
Reaction Steps
A mixture of 57.0 g of propiophenone in 150 ml of N,N-dimethylformamide dimethyl acetal was stirred and heated at reflux for 24 hours. Then the solvent was removed in vacuo to give a yellow oil. The oil was subjected to Kugelrohr distillation to give 69.8 g of 3-dimethylamino-2-methylacrylophenone as a yellow oil, B.P. 100° C. (0.050 mm Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04916137 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-fc4a2657bf6e463882653fd03755c3aa |
| Source note | uspto-grants-1990_04 |