Thiophosgene → Benzimidazole

HRID 2073227Notes

Reaction equation

HRID 2073227 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8]N.O(CC)[C:11]([S-])=S.[K+].C(Cl)(Cl)=S>>[N:8]1[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH:1][CH:11]=1

Participants

4

Reactant 3

HCID 10040ThiophosgeneHCID 2723987HCID 2723987, compoundHCID 2735045Potassium ethylxanthate

Product 1

HCID 5798Benzimidazole

Procedure

In the process (b) of the invention, a 2-aminophenylhydrazine derivative of the formula (IVb) is reacted with carbond disulfide, potassium ethyl xanthate or thiophosgene to give a benzimidazole derivative of the formula (Ie) according to the Reaction Scheme (C).

Sources & evidence

ORD record
ord-c898c14c1a824ff3a4d3195f830bebf0
Source dataset
uspto-grants-1990_04
Patent number
US04916149

Reaction notes

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