Formic Acid → HCID 86743848, compound

HRID 2073241Notes

Reaction equation

HRID 2073241 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:5]=1[NH:14][NH2:15])([O-:3])=[O:2].[CH:16](O)=[O:17]>O>[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:11])([F:12])[F:13])[CH:7]=[CH:6][C:5]=1[N:14]([CH:16]=[O:17])[NH2:15])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 284Formic AcidHCID 38380972-nitro-4-(trifluoromethyl)phenylhydrazine

Product 1

HCID 86743848HCID 86743848, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

64 g of 2-nitro-4-trifluoromethylphenylhydrazine [prepared as described in: J. Org. Chem. 42, 542 (1977)] were heated with 200 ml of 85% formic acid in a water bath for 90 minutes. After cooling down, the yellow solution was poured into 250 ml of water. The crystalline precipitate was filtered by suction, washed with water and dried at 80° C. to yield 72 g (98%) of 2-nitro-4-trifluoromethyl-N-formylphenylhydrazine, m.p.: 152°-153° C.

Workup

  1. temperatureAfter cooling down
  2. filtrationThe crystalline precipitate was filtered by suction
  3. washwashed with water
  4. customdried at 80° C.

Sources & evidence

ORD record
ord-ab846f6f0736429d826eeb0c5e63cb26
Source dataset
uspto-grants-1990_04
Patent number
US04916149

Reaction notes

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