Lysine Monohydrate → HCID 67863549, compound

Participants

Reaction Steps

A mixture of L-lysine hydrate (4.01 g) and (2S,4R)-2-[(Z)-5-carboxy-1-pentenyl]-1-(4-chlorophenyl- sulfonyl)-4-(4-chlorophenylsulfonylamino)pyrrolidine (12.0 g) was dissolved in a mixture of hot water (9 ml) and hot ethanol (170 ml) and the solution was cooled to room temperature. The precipitate (white crystal) was collected by filtration, washed with ethanol and dried in vacuo to give L-lysine salt of (2S,4R)-2-[(Z)-5-carboxy-1-pentenyl]-1-(4-chlorophenylsulfonyl)-4-(4-chlorophenylsulfonylamino)pyrrolidine (13.4 g) as white crystals.

Provenance & Evidence