HuagongsheHuagongshe Chemistry Print Report · For research reference only
[1-[3-(3-Pyridinyl)propyl]-4-(3-pyridinyl)butyl]carbamic acid 1,1-dimethylethyl ester → alpha-[3-(3-Pyridinyl)propyl]-3-pyridinebutanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [1-[3-(3-Pyridinyl)propyl]-4-(3-pyridinyl)butyl]carbamic acid 1,1-dimethylethyl ester | HCID 15097556 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | alpha-[3-(3-Pyridinyl)propyl]-3-pyridinebutanamine | HCID 14994128 | 80% |
Reaction Steps
As in Example 133 hydrolysis of 5.4 g of [1-[3-(3-pyridinyl)-propyl)-4-(3-pyridinyl)butyl]carbamic acid 1,1-dimethylethyl ester in 55 mL of 1N HCl yielded 3.15 g of alpha-[3-(3-pyridinyl)propyl]-3-pyridinebutanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04916145 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-8962787b98a64ca091315ea7463d6d9e |
| Source note | uspto-grants-1990_04 |