HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Benzo[b]furan-3-ylethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzofuran-3-acetonitrile | HCID 2769401 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Benzo[b]furan-3-ylethylamine | HCID 12420812 | — |
Reaction Steps
A solution of 3.97 grams (0.025 mole) of 3-cyanomethylbenzo[b]furan in 200 milliliters of diethyl ether was slowly added to a refluxing suspension of 3.84 grams (0.1 mole) of lithium aluminum hydride in 400 milliliters of ether and the mixture was heated 3 hours, then cooled and water was slowly added. The suspension was filtered and the filtrate was evaporated to obtain an oily product, the hydrochloride salt of which has m.p. 183°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04916223 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-f636aa1af8874a8d9c033c4cbc0b1eb7 |
| Source note | uspto-grants-1990_04 |