HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chlorophenyl)acetic acid → 4-Chlorophenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 4-Chlorophenylacetyl chloride | HCID 90692 | 97.4% |
Reaction Steps
A mixture of 200 g of 4-chlorophenyl acetic acid, 178.5 g of thionyl chloride and 600 ml of benzene was heated at reflux for 6 hours and then concentrated in vacuo. The residue was vacuum distilled, giving 215.8 g of 4-chlorophenyl acetyl chloride, bp 94°-95° C. (2.5 mmHg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04916237 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-efb119d5682946cf8678837844396b0e |
| Source note | uspto-grants-1990_04 |